Bangalore - Milan Workshop
Date : April 6-8, 2009
Venue: National Centre for Biological Sciences, TIFR on April 6th and 7th
Jawaharlal Nehru Centre for Advance Scientific Research on April 8th
Program
DAY 1 (6th April, 2009)
9:15 a.m.
Introductory Talk by K. VijayRaghavan, Director, NCBS: 15 minutes
Introductory Talk by Pier Giuseppe Pelicci, Director, European Institute of Oncology: 10 minutes
Introductory Talk by Marco Foiani, Director, IFOM, FIRC Institute of Molecular Oncology: 10 minutes
Session 1: Model Systems in Disease (Chair: Sudhir Krishna)
Luisa Lanfrancone (IFOM-IEO): RaLP in melanoma genesis and progression
Guruprasad Reddy Sure (NCBS): The complex roles of the JNK signaling scaffold molecule, UNC-16, in regulating mitochondrial distributions in neurons
Rajnish Rao (NCBS): In search of an animal model of PTSD
COFFEE/TEA
11:30 a.m.
Session 2: Genomes and Evolution (Chair: Jayant Udgaonkar)
Dipankar Chatterji (IISc): Towards designing single round transcription in prokaryotes on immobilized templates
Odity Mukherjee (NCBS): Evolutionarily based haplotype analyses of MAPT locus in sporadic taupathies
Uma Ramakrishnan (NCBS): Demographic history and Evolution in the Indian subcontinent: lessons from a comparitive phylogeographic approach for mammals
LUNCH
2:00 p.m.
Session 3: Cell Biology (Chair: Gaiti Hasan)
Sandhya Koushika (NCBS): The stability of the anterograde synaptic vesicle motor,
UNC-104, depends on its ability to bind cargo
Neha Vyas (NCBS): Nanoscale organisation of Hedgehog and long range signaling
Giorgio Scita (IFOM-IEO): Membrane and actin dynamics in the spatial control of signaling during cell migration
Sudha Kumari (NCBS): Post-endocytic sorting of GPI-anchored proteins
COFFEE/TEA
4:00 p.m.
Session 4: Replication and Repair (Chair: Mathew K Mathew)
Marco Foiani (IFOM-IEO): Mechanisms controlling genome integrity during S phase
Namrata Jayant (NCBS): Elucidating substrate specificity of repair enzymes using UV resonance Raman spectroscopy
K. Muniyappa (IISc): Holliday Junction Binding and Processing by Meiosis-Specific Saccharomyces cerevisiae Hop1 Protein
Abani Kanta Naik (IISc.): Mechanism of RAG cleavage on altered DNA structures: a potential threat to genomic stability
Deepak Nair (NCBS): Structural Basis of DNA Lesion bypass by human DNA Polymerase iota
DAY 2 (7th April, 2009)
9:15 a.m.
Session 1: Signaling and Development (Chair: Maneesha Inamdar)
Mamta Jain (JNCASR): Dissecting the role of rudhira in angiogenesis
Gayatri V (NCBS): Intracellular Ca2+ signaling in the Insulin producing cells of Drosophila
Elisabetta Dejana (IFOM-IEO): The role of Wnt signaling in vascular development
Vani Kulkarrni (JNCASR): Asrij plays a role in hematopoiesis and immunity in Drosophila melanogaster
Pinky Kain (NCBS): Olfactory transduction mechanisms in Drosophila melanogaster
COFFEE/TEA
11:15 p.m.
Session 2: Cancer/Translational Aspects I (Chair: Seema Nanda)
G. Mc Vie (IEO): Translational Research, Challenges and Pitfalls
Devaveena Dey (IISc): Stem Cells and Breast Cancer
Tessy Maliekal (NCBS): Cervical Cancer Spheres and Tumor Properties
Tapas Kundu (JNCASR): Histone Chaperone in Transcription Regulation and Cancer Manifestation: Role of NPM1
Suvasini R (IISc): Differential regulation of DNA damage induced cytotoxicity and cell death by PI3 kinase: Role for p53 and its implications in cancer chemotherapy
LUNCH
2:15 p.m.
Session 3: Chromatin and Signaling (Chair: G. V. Shivashankar)
Arif (JNCASR): Chromatin Modifications Linked to Oral Cancer: a Potential Target for Therapeutics
Pawan Singh (IISc): Mycobacterium leprae RecA intein: a LAGLIDADG homing endonuclease, displays a unique mode of DNA binding and catalysis compared to a canonical LAGLIDADG homing enzyme
Pier Giuseppe Pelicci (IFOM-IEO): Epigenetic treatment of leukemias
Mridula Nambiar (IISc): Molecular Mechanism of Chromosomal Translocations in Lymphoma and Leukemia
COFFEE/TEA
3:45 p.m.
Session 4: Protein and DNA structure and function (Chair: Yamuna Krishnan)
Raghavan Varadarajan (IISc): Design of temperature-sensitive and inactive mutants to understand gene function
Spriha Gogia (NCBS): Studying enzyme active-site interactions using Raman spectroscopy
Jasbir Singh (IISc): Mycobacterium tuberculosis RuvA Induces Two Distinct Types of Structural Distortion between the Homologous and Heterologous Holliday Junctions
Mathew K. Mathew (NCBS): Moving Ions across Biological Membranes
Souvik Modi (NCBS): I-switch: A DNA nanomachine as a cellular reporter
Ruchika Sharma (IISc): RecJ exonuclease and SSB interact physically and functionally
DAY 3 (8th April, 2009) at JNCASR
9:30 a.m.
Session 1: Cancer/Translational Aspects II (Chair: Tapas Kundu)
Sasikala (NCBS): Regulation of NOTCH1 signaling by deubiquitination
Soumitra Das (IISc): p53 and little brother p47-linking synthesis with protein function
Mohan Kumar (IISc): Proteomic Identification of Haptoglobin as a Glioblastoma Serum Biomarker: Implications in Cancer Chemotherapy
Vaijayanti Gupta (Strand Life Sciences Pvt. Ltd.): Prognostic and signaling pathway based characterization of breast cancer subtypes
COFFEE/TEA
11:30 p.m.
Session 2: Stem Cells and Signaling (Chair: Mitradas Panicker)
Francesco Blasi (IFOM-IEO): Prep1: A novel Tumor Suppressor and Stemness gene
Jeevisha Bajaj (NCBS): Notch signaling in cervical cancer stem-like cells
Pier Giuseppe Pelicci: Regulation of self-renewal in cancer stem cells
Lakshmi P (NCBS): A hierarchical signaling cascade involving Notch and the mTOR – Rictor complex regulates neglect- induced death in mammalian cells