Sympotein VII - Macromolecular Structures and Function: How do they Connect?

Coordinator:

R. Sowdhamini,
NCBS-TIFR,
Bangalore

After learning about Rhythms lets immerse ourselves into Structures and Folds: Sympotein VII (18th August 2010) on "Macromolecular Structures and Biology -How do they connect?"

This is the time when we all will aim to once again revive the rattling thought by Francis Crick "Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself." Sympotein VII offers the opportunity to clench the connection between macromolecules and their Biology.

The design is therefore to learn about the following themes:

1.Detailed mechanism of action revealed along with amazing chemistry due
to availability of crystal structure.

2.Remarkable substrate specificity and how is this achieved ?

3.Dramatic allostery upon binding giving rise to dimerisation (eg. kit
receptor).

4.Biologically relevant conformational changes evidenced due to the
availability of multiple crystal structures of one protein.

5.Protein superfamily relationships and clues of biological function upon
structure determination - impact on evolution.

6.Point mutations and dramatic differences in structure and function
evidenced by crystallography.

7.A long-time story of interactions, binding, specificity and mechanism of
action (ribosome, for example)

8.Structural Genomics Initiative.

9.Novel folds and new functions.

and many more...

For Downloading poster click here .